We invite you, over the course of the next ten articles, to consider the ways in which the world around you has changed, and how those changes have affected you. One of these avenues of change provided us with the guiding theme for this semester’s issue: plasticity. The brain’s plasticity—its ability to physically adapt to both minute and radical alterations in the environment—underlies many of the wondrous things we can accomplish: from learning to play the piano to recovering from devastating injuries.